Bucyrus graduate trying to develop Alzheimer's drug receives $2M research grant


BUCYRUS – A Bucyrus High School graduate has received a $2 million research grant to develop a new drug for Alzheimer’s disease.

Dr. Issac Schiefer, an assistant professor at University of Toledo, received the grant from the National Institute on Aging for his latest research in April. At 32, he is one of the youngest to receive the grant. 

“The grant makes it so we can finally do full scale drug development,” he said.  

Schiefer said that his research has been focused around a molecule he has discovered that is the first of its type to slow and in some cases reverse of Alzheimer’s in mice. Further research is needed to make sure the science could be developed into a safe and effective drug. 

More: Bucyrus graduate’s Alzheimer’s research shows promise

Schiefer’s hope is that the research will lead to a new drug that could help slow or reduce memory deficits in humans with Alzheimer’s disease and dementia. 

“I’d love to be able to put a drug on the market from UT,” he said. 

He said that he’s not looking to necessarily cure the disease, but provide a slight improvement. The Alzheimer’s Research Association currently says that there are only five FDA approved drugs for the disease. 

He was inspired to do the research as both a native of Bucyrus and his personal experience, as his grandfather battled Alzheimer’s when he was a teen. 

“Our population, because of the demographic, is going to be more impacted,” he said.  

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