Research may help rescue antibiotics' effectiveness in the face of drug-resistant bacteria

Research may help rescue antibiotics' effectiveness in the face of drug-resistant bacteria

BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care. Bacteria–especially Gram-negative strains–are becoming increasingly resistant to current antibiotic drugs, and the development of new classes of antibiotics has slowed. Faced with these challenges, investigators are studying the potential of combination therapy, in which two or more drugs are used together to increase […]

New Drug Shows Promise to Improve Kidney Malfunction

New Drug Shows Promise to Improve Kidney Malfunction

Researchers in Colorado are studying an experimental drug to treat a rare genetic disease with no cure that affects the kidneys. He is a father of two who is taking part in the promising clinical trial. Scott Hinerfeld is an avid cyclist, climber and snowboarder. But 2 years ago, the father of two was struggling. […]

New Medications May Increase Available Organs for Transplant

New Medications May Increase Available Organs for Transplant

After her kidneys failed from the same illness that took the lives of her mother and brother, Anne Rupp went on dialysis in May 2016, spending three hours a day, three times a week undergoing the blood-cleaning procedure. She hated it. Rupp, who had polycystic kidney disease, joined more than 95,000 other Americans on kidney […]

The first human trials of this experimental, cancer-killing drug could change everything

The first human trials of this experimental, cancer-killing drug could change everything

CLOSE If you saw Bob Rulli on the street, you’d never guess he had cancer. He’s the first person to receive a first-of-its-kind drug made in Cincinnati. Kareem Elgazzar, kelgazzar@enquirer.com Bob Rulli undergoes a transfusion of the experimental drug BXQ-350, which lasted about an hour, Tuesday, July 10, 2018, at the University of Cincinnati’s Barrett […]

Americans Fund Most of the World's Drug Research. Here's How Trump Can End That

Americans Fund Most of the World's Drug Research. Here's How Trump Can End That

President Donald Trump recently released an ambitious, 44-page plan to drive down prescription drug prices. The blueprint relies, in part, on negotiating and enforcing trade deals to prevent other countries from freeloading off of American researchers. That’s a smart strategy. Right now, most of our trading partners impose government price controls on drugs. Ensuring that […]

Revolutionary new view of how living cells make energy

Revolutionary new view of how living cells make energy

Mitochondria. Credit: Wikipedia commons Researchers at The University of Western Australia and Harry Perkins Institute of Medical Research have made a fundamental discovery about of the atomic structure and function of the biological ‘factories’ in cells that make energy, providing a new means to target the ‘machines’ within factories for drug treatments. Just as cars […]