Otsuka to acquire antibody developer Visterra in $430M deal

Otsuka to acquire antibody developer Visterra in $430M deal

Otsuka Pharmaceutical plans to acquire previous Fierce 15 winner Visterra and its antibody engineering platform for $430 million in cash, as Otsuka looks to build out proprietary drug discovery and development efforts across its programs, including in nephrology and other difficult diseases. The deal follows Visterra’s aborted $50 million IPO attempt, pulled in February of […]

Enzyme discovery could help in fight against TB

Enzyme discovery could help in fight against TB

IMAGE: NagA protein crystals. view more  Credit: University of Warwick Research by a team led by Dr Elizabeth Fullam, has revealed new findings about an enzyme found in Mycobacterium tuberculosis (Mtb) the bacterium that causes TB. TB causes more deaths than any other infectious disease, including from HIV and malaria. In 2016 there were 10.4 million […]

Enzyme discovery could help in fight against tuberculosis

Enzyme discovery could help in fight against tuberculosis

Credit: University of Warwick An enzyme structure discovery made by scientists at the University of Warwick could help to eradicate tuberculosis (TB). Research by a team led by Dr. Elizabeth Fullam, has revealed new findings about an enzyme found in Mycobacterium tuberculosis (Mtb) the bacterium that causes TB. TB causes more deaths than any other […]

Mature kidney podocytes for developing cell therapies and drug discovery

Mature kidney podocytes for developing cell therapies and drug discovery

By Lindsay BrownellJuly 11, 2018 New protocol produces large numbers of mature human podocytes, enabling kidney disease modeling, drug discovery, and potential cell therapies Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the […]

Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in …

Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in …

Jump to SectionIntroductionMethodsResultsDiscussionSupplementary MaterialReferences To our knowledge, our study was the first to attempt non-invasive ultrasound-mediated targeted hyperthermia for triggered drug release and enhanced drug delivery in a clinical setting. Apart from the existing risks associated with general anaesthesia, the overall intervention posed no additional safety concerns to the patient other than those typically associated […]

New report says individual research results should be shared with participants more often

New report says individual research results should be shared with participants more often

WASHINGTON – When conducting research involving the testing of human biospecimens, investigators and their institutions should routinely consider whether and how to return individual research results on a study-specific basis through an informed decision-making process, says a new report from the National Academies of Sciences, Engineering, and Medicine. Decisions on whether to return individual research […]