Cancer-fighting drugs also help plants fight disease

Cancer-fighting drugs also help plants fight disease

The effect of different concentrations of actinomycin D applied to pea tissue. The top image is lower concentration of the drug, the bottom the highest concentration. Credit: WSU Cancer-fighting drugs used on humans can help plants fight disease as well. That discovery, by two Washington State University plant pathologists, could help scientists develop new pathways […]

Cancer drug delivery closes in on fabled 'magic bullet'

Cancer drug delivery closes in on fabled 'magic bullet'

Researchers have demonstrated that specialized nucleic acid-based nanostructures could target cancer cells while bypassing normal cells. “Most of the therapeutic drugs are not able to discriminate the cancer cells from healthy cells…” More than 100 years ago, German Nobel laureate Paul Ehrlich popularized the “magic bullet” concept—a method that clinicians might one day use to […]

Targeting the growth signals of 'undruggable' cancers

Targeting the growth signals of 'undruggable' cancers

Dr Bivona and his team showed that the growth of multiple cancers slowed by suppressing the signalling pathway using an experimental compound… The RAS/MAP kinase (MAPK) signalling pathway has previously been labelled by some scientists as ‘undruggable’, but a team of researchers may have identified a method of successfully decoupling the pathway from external growth […]

Copy Number Abnormalities May Inform Survival, Drug Resistance

Copy Number Abnormalities May Inform Survival, Drug Resistance

August 13, 2018 For cancers associated with numerous copy number changes, it is difficult to assign disease classifiers and identify useful targets for drug development. In a study published in Nature Genetics, researchers showed that categorizing copy number abnormalities into distinct sets from […]

FDA expands blood pressure drug recall due to cancer concerns

FDA expands blood pressure drug recall due to cancer concerns

The U.S. Food and Drug Administration is expanding a recall of drug products containing the ingredient valsartan, which is used to treat high blood pressure and heart failure. The FDA first issued a voluntary recall in July after results from laboratory tests revealed that some drugs may have been tainted with the substance N-nitrosodimethylamine or […]

New ovarian cancer medicine approved for use by NHS Scotland

New ovarian cancer medicine approved for use by NHS Scotland

The approval of a new drug to treat ovarian cancer in Scotland has been welcomed by campaigners. The Scottish Medicines Consortium (SMC) has accepted niraparib (Zejula) for use by NHS Scotland for advanced ovarian cancer. It is said to be the first maintenance treatment for patients with ovarian cancer who do not have the BRCA mutation […]

Blood pressure drug recalled for cancer concerns

Blood pressure drug recalled for cancer concerns

A popular blood pressure and heart medication known as Valsartan Tablets has been recalled due to possible carcinogen contamination.  The Food and Drug Administration announced last week that all Valsartan Tablets, which come in sizes ranging from 40 mg to 320 mg, were being recalled because trace amounts of cancer-causing agents were detected. Nitrosodimethylamine, or NDMA, a substance […]